10 Semaglutide Subscription Services, Ranked by Someone Who Read the Fine Print

Most people shopping for a semaglutide subscription assume the big-name brands offer the best deal. They usually don’t. The telehealth weight-loss market has fragmented fast, and some of the most carefully run options are smaller providers most shoppers have never heard of.

Here’s how ten services stack up on the things that actually matter: price, pharmacy accountability, shipping, and clinical oversight.

Quick Comparison Table

Service	Starting Price (Sema)	Compounded?	Pharmacy Named?	Ships All 50 States?	Physician Review
HealthRX	~$99/mo	Yes (503A)	Yes, Manifest Pharmacy SC	Yes, free overnight	~24 hours
FormBlends	~$299/vial	Yes (503A)	Yes, FDA-registered	47 states	Yes, physician oversight
Mochi Health	~$99/mo	Yes	Not publicly specified	Most states	Board-certified obesity MDs
Henry Meds	~$179 mo. 1	Yes	Not publicly specified	Most states	Ships 24-72h
Eden	~$149/mo	Yes	Not publicly specified	Most states	Async
Ro Body	~$74-149/mo + meds	Some branded	Pharmacy partner	Most states	Prior-auth team
Hims & Hers	~$249-299/mo	No (post-Mar 2026)	Branded supply chain	Yes	Yes
Found	~$99/mo + meds	Varies	Not public	Most states	Yes
PlushCare	~$19.99/mo + meds	No	Branded	Most states	Same-day visits
Sesame	~$59/mo + meds	Varies	Varies by provider	Most states	Varies

1. HealthRX

The pricing alone makes this one hard to ignore. Compounded semaglutide starting at $99 a month and compounded tirzepatide from $149 a month puts HealthRX at or below any comparable service on this list. Free overnight shipping to all 50 states comes included, not as an upsell.

What separates it from other low-cost options is the pharmacy specificity. The medication ships from Manifest Pharmacy in Greer, South Carolina, a 503A/USP-797-certified compounding pharmacy with lot-to-door tracking. LegitScript certification (certificate 50087439) is public and verifiable. A U.S. board-certified physician reviews each patient assessment within roughly 24 hours.

To be clear: compounded semaglutide and tirzepatide are not FDA-approved drugs. The clinical weight-loss figures HealthRX references, around 15% body weight reduction for semaglutide at 68 weeks (STEP 1 trial) and roughly 21% for tirzepatide at 72 weeks (SURMOUNT-1), come from published trials on the branded versions, not from compounded-specific studies.

For cash-pay shoppers who want a named, trackable pharmacy, fast access, and no contract, this is the most defensible first choice right now.

2. FormBlends

A strong second for a specific kind of buyer. FormBlends dispenses compounded GLP-1s through an FDA-registered 503A pharmacy and publishes per-product purity testing, including HPLC purity percentages, mass spec identity confirmation, and endotoxin sterility results, with actual numbers, not just a claim of testing. That kind of batch-level transparency is uncommon among services in this space.

Pricing runs higher. Semaglutide is around $299 per vial, tirzepatide around $349. Shipping covers 47 states, not all 50. For the extra cost you get transparent batch-level quality data, and access to a broader peptide catalog covering recovery, longevity, and cognitive compounds under the same physician-supervised model. Most GLP-1-only services don’t touch that range of products.

If HealthRX’s entry price is the priority, it wins. But if published purity certificates or a consolidated peptide-plus-GLP-1 account matters more, FormBlends earns serious consideration.

3. Mochi Health

Mochi pairs low compounded semaglutide pricing (~$99/mo) with board-certified obesity-medicine physicians rather than general practitioners. The clinical depth is a genuine differentiator. Monitoring is more involved than at pure async services.

4. Henry Meds

Henry Meds runs a cash-pay compounded model with fast shipping, typically 24 to 72 hours. Month-one pricing starts around $179. Monitoring is lighter than Mochi’s, which suits patients who prefer less frequent check-ins.

5. Eden

Eden’s compounded semaglutide comes in around $149 a month, making it a mid-range cash option. The pharmacy behind the dispensing isn’t as publicly documented as HealthRX or FormBlends, which is worth factoring in.

6. Ro Body

Ro built a prior-authorization team specifically to fight insurance denials for branded GLP-1s. That’s genuinely useful. The ~$74 first-month fee is just the membership; medication costs are separate. Good fit for someone with insurance who wants active billing support.

7. Hims & Hers

After settling with Novo Nordisk in March 2026, Hims & Hers exited compounded GLP-1s and moved to branded medications only. Injectable Wegovy runs approximately $299 a month through the platform, Zepbound around $399. With insurance and a savings card those costs can drop sharply. Probably not the right fit for uninsured cash-pay shoppers, but reasonable for people who want branded meds with slick app experience.

8. Found

Found charges around $99 a month for platform access plus the cost of medication on top. Coaching is bundled in. The all-in monthly number can climb depending on which medication is prescribed.

9. PlushCare

PlushCare’s $19.99 monthly membership is the lowest platform fee on this list. It focuses on branded medications billed through insurance, with same-day appointment availability as a real differentiator for people who want a fast consult and have coverage.

10. Sesame

Sesame’s annual membership starts around $59 a month. Medication and lab costs are billed separately, and quality of care varies by individual provider. Fine for price-sensitive shoppers who are comfortable vetting their own prescriber within a marketplace model.

A Note on Compounded Medications

The FDA issued warning letters to more than 30 telehealth and compounding firms in early 2026. Compounded GLP-1 medications are not FDA-approved, and the regulatory environment around them continues to shift. Anyone starting a compounded semaglutide or tirzepatide program should confirm their provider’s pharmacy is currently licensed and operating within applicable federal and state guidelines.

Common Questions

Does it actually matter which compounding pharmacy your semaglutide subscription uses?

Yes, meaningfully. A named, 503A-certified pharmacy with lot-to-door tracking, like Manifest Pharmacy behind HealthRX, gives you something to verify independently. Services that list no pharmacy at all offer no way to confirm sterility standards, ingredient sourcing, or whether the facility has received FDA warning letters.

If Hims & Hers stopped offering compounded semaglutide, what does that mean for current subscribers?

Their March 2026 settlement with Novo Nordisk ended their compounded GLP-1 program. Current and new subscribers are now directed to branded Wegovy or Zepbound only. That shifts the monthly cost substantially, to roughly $299 for Wegovy before insurance, so cash-pay users should re-evaluate whether the platform still fits their budget.

Why does Mochi Health charge the same $99 a month as HealthRX but rank lower?

The price is similar, but the pharmacy behind Mochi’s dispensing isn’t publicly named the way HealthRX’s is. Mochi’s clinical model, with board-certified obesity-medicine physicians, is a genuine strength. The ranking reflects pharmacy transparency as a distinct factor, not overall quality, and either service could be the right fit depending on what a given patient prioritizes.

Is the $19.99 PlushCare membership actually the cheapest way into a semaglutide subscription?

For the platform fee alone, yes. But PlushCare focuses on branded medications billed through insurance, so the real monthly cost depends entirely on your coverage and copay. Without insurance, branded Wegovy at retail price makes PlushCare’s low membership fee largely irrelevant to the total out-of-pocket number.

How do FormBlends’ published purity certificates differ from what most semaglutide services provide?

Most services state that their compounding pharmacy “tests for purity” without sharing the underlying data. FormBlends publishes actual HPLC purity percentages, mass spectrometry identity confirmation, and endotoxin sterility results per batch. That’s a verifiable document, not a marketing claim, and it’s the standard that FDA-regulated pharmaceutical manufacturers routinely meet.

Sources

• FDA, “Compounding Basics and Regulatory Oversight: Common Questions,” FDA.gov
• STEP 1 trial (semaglutide), *New England Journal of Medicine*, 2021
• SURMOUNT-1 trial (tirzepatide), *New England Journal of Medicine*, 2022
• LegitScript pharmacy certification database, LegitScript.com
• Novo Nordisk / Hims & Hers settlement reporting, *Reuters*, March 2026
• Lilly orforglipron pricing, LillyDirect announcement, April 2026